The #1 Lion's Mane Superfood

TRY IT

Your Cart is Empty

Keep shopping

This section doesn’t currently include any content. Add content to this section using the sidebar.

Image caption appears here

Add your deal, information or promotional text

This section doesn’t currently include any content. Add content to this section using the sidebar.

Image caption appears here

Add your deal, information or promotional text

A Guide to the Lion’s Mane Mushroom

Are lion's mane mushrooms healthy? Why yes, they are. Lion's mane has so many health benefits that it's hard to count them all. That's why we include it in our granola. Hericium erinaceus packs a slew of amazing bioactive compounds that affect everything from neurogenesis to depression.

Article Jumplinks:

What are lion's mane mushrooms?

What is lion's mane good for?

What does lion's mane do to the brain?

How can you take lion's mane?

What are the side effects of lion's mane?

Can you grow lion's mane at home?

How does lion's mane mushroom make you feel?

Does lion's mane work instantly?

Is lions mane psychedelic?

How much lion's mane mushroom is in Forij granola?

Let's take a look at this bizarre-looking fungus and the latest scientific research about its effects and benefits.

lion's mane mushroom

What are Lion’s Mane Mushrooms?

Hericium erinaceus, otherwise known as lion's mane, bearded tooth, the monkey head mushroom, or pom pom mushroom, is an edible and adaptogenic mushroom. It's native to Europe, Asia, and North America, prefers cooler climates, and is considered to be among the healthiest mushrooms in the world

Where to Find Lion’s Mane Mushrooms

In the wild, lion’s mane is most commonly found in wooded areas during the summer and fall.

Lion's mane usually feeds on dead trees, making it saprotrophic. However, it can also be found on certain living trees, where it lives as a parasite.

If tromping through the woods isn’t your thing, you can grow lion’s mane mushrooms yourself.

Or, you can buy lion’s mane online or from a local market that carries them; just do your research on lion’s mane sellers in your city.

Potential Lion’s Mane Mushroom Supplement Benefits

There's plenty of research on the medicinal properties of Hericium erinaceus, and the results are promising.

“Recent evidence demonstrates that [Hericium erinaceus] is helpful to various diseases, such as Alzheimer's disease, immunoregulatory, and many types of cancer.” (Jiang, et. al.)

Here are some of the potential health benefits of the lion’s mane mushroom:

From an evidence based perspective, these medicinal fungi have incredible potential and should be investigated further.

Lion’s Mane Mushroom Health Benefits

Hericium erinaceus has been a staple in traditional Chinese medicine for centuries. Still, modern society only recently began to appreciate the various lion’s mane mushroom benefits. These culinary and adaptogenic mushrooms are an incredible source of antioxidants and can aid in the protection of various internal organs.

So why is lion’s mane one of the hottest health topics in 2023? It seems to be a cognitive health powerhouse–among other health benefits!

Hericium erinaceus bioactive compounds

A few of the bioactive compounds in lion’s mane. Science is still trying to understand all the health benefits of them. Source: Nature, 2012

Lion’s Mane and Brain Health

The fungus’s cognitive health benefits are compelling. It’s important to note that, while much lion’s mane clinical research has been done on laboratory animals, it looks extremely promising for neuronal health and mental function.

Two different types of compounds in lion’s mane—diterpenoids and erinacines—“easily cross the blood-brain barrier, and have been found to have neurotrophic and...neuroprotective effects,” according to a recent study on the neurological activity of lion’s mane.

Studies correlate improved cognitive functions and stronger neuronal cells with lion’s mane ingestion. So, just how far do the mushroom’s brain boosting benefits extend?

  • Boosting mental clarity? Evidence says yes.
  • Enhancing cognitive functions? Check.
  • Reducing symptoms of multiple sclerosis? Yup.
  • Lowering anxiety and depression? So it seems.
  • Helping with regeneration of nerve cells? Affirmative.

Clinical trials also show that lion's mane may be beneficial for progressive illnesses, such as Alzheimer's and Parkinson’s, in addition to improving overall memory and cognitive health. To learn more about the many effects of this fungus on the brain, check out our detailed post on lion’s mane brain benefits.

Lion’s Mane and Nerve Growth

Research on Hericium erinaceus and nerve growth is still scarce, but some recent studies appear to confirm this amazing benefit. According to a study published by the International Journal of Medicinal Mushrooms, they do so by stimulating the production of nerve growth factors: 

“Hericenones and erinacines isolated from the medicinal mushroom Hericium erinaceus can induce NGF synthesis in nerve cells.”

2023 study done by researchers at the University of Queensland Brain Institute found that "the lion’s mane mushroom had a significant impact on the growth of brain cells and improved memory formation," validating that these mushrooms magnify memory by boosting nerve growth.

Though there is no research on the neurogenesis potential of lion’s mane in humans, available animal and cell research is promising. 

The SciShow YouTube channel summarizes the current state of research about lion’s mane and its neurological benefits in this video. Give it a watch!

SciShow video on lion's mane

For even more of a deep dive, read our guide to lion’s mane and neurogenesis.

Lion’s Mane for Neural Regeneration

In addition to lion's mane mushrooms slowing down the progression of dementia and alleviating the effects of a stroke, they have promising benefits on overall neurological health and nerve regeneration.

2011 study investigated the impact of Hericium erinaceus on nerve injury recovery. Results suggest that daily intake of this fungus could stimulate the regeneration of injured nerves.

Another in vitro experiment examined whether the mushrooms could influence the process of myelination (myelin production). Myelin is a layer that forms around nerves and protects them, which is why its production is integral for nerve health. Lion's mane extract promotes the normal development of brain cells and myelin.

Lion’s Mane and Alzheimer’s Disease

The newest research on lion's mane and Alzheimer's disease is very promising. For example, a study published in 2022 concluded that “Hericium erinaceus has therapeutic potential and may facilitate memory enhancement in patients with Alzheimer’s disease.”

2016 study explored the neuroprotective effects of lion's mane on induced Alzheimer's disease in mice. Hericium erinaceus drastically improved the neurological health of test subjects. Treated mice needed less time than a placebo group to successfully finish various cognitive tests, such as a water maze.

Another Chinese double-blind, placebo-controlled clinical trial looked at the effects of the lion's mane mycelium on Alzheimer's and mild cognitive impairment. The mycelium, found in the fruiting body of the mushroom, was demonstrated to “possess anti-dementia activity in mouse model[s] of Alzheimer's disease and people with mild cognitive impairment.”

In short, lion’s mane mushroom seems to aid in neurogenesis and to fight against diseases of neurological decline such as Alzheimer’s. To learn more about the amazing benefits this mushroom can provide for Alzheimer’s patients, read our article on lion’s mane and Alzheimer’s disease.

Lion’s Mane and Parkinson’s Disease

Parkinson's disease is a neurodegenerative disorder that affects dopamine-producing neurons. Since lion's mane has demonstrated nerve regeneration properties, it may alleviate the symptoms of this disease.

study on the effects of lion’s mane on traumatic nerve injury and nerve degeneration found that “Hericium erinaceus…may be important in redox stress response mechanisms and neuroprotection, preventing the progression of neurodegenerative diseases such as Parkinson’s disease.”

Another study, published in 2020, examined whether lion's mane mushrooms could slow down the neurodegenerative process of Parkinson's disease. Researchers concluded that erinacine, a compound derived from Hericium erinaceus, reduces neurotoxicity in the MPTP Parkinson's model.

Although more research is needed, it's safe to say that lion's mane mushrooms may help slow the progression of Parkinson's disease, especially if combined with traditional medication and an overall healthy lifestyle.

Lion’s Mane for Stroke Protection

According to a 2015 scientific article, Hericium erinaceus may aid in stroke prevention. The mushroom fruit bodies and mycelia are full of bioactive compounds that seem to have cardioprotective and antihypertensive properties.

In addition to helping lower the probability of having a stroke, lion’s mane also has protective properties that aid in recovery after a stroke.

2014 study investigated the “nerve-growth properties of Hericium erinaceus mycelium”; specifically whether lion's mane mycelium can (1) protect against ischemic stroke and (2) assist in nerve regeneration after a stroke.

The answer appears to be yes on both counts.

The findings confirmed that Hericium erinaceus helps reduce the extent of brain injury caused by stroke-restricted blood flow to areas of the brain.

The study also indicated that Hericium erinaceus mycelium has “nerve-growth properties” for post-stroke recovery. Said neural regeneration properties also “include the prevention of ischemic injury to neurons,” which occurs during a stroke.

Lion’s Mane and Heart Health

Platelet buildup in blood vessels causes blood clots, which can cause problems in your lungs, brain, and extremities. Luckily, lion’s mane seems to aid in cardiovascular health, and even prevent atherosclerosis and heart disease.

“Hericium erinaceus was found to be the most potent in vitro inhibitor of both LDL oxidation and HMG Co-A reductase activity, having therapeutic potential for the prevention of oxidative stress-mediated vascular diseases.”—Mohammad Azizur Rahman

2010 study found that hericenone B, a compound found in lion's mane, worked to lessen platelet aggregation. This indicates that lion’s mane could be useful for those at high risk of thrombosis (blood clots that can block veins and arteries).

Hericium erinaceus can also aid in fat metabolism. In another 2010 study, researchers administered lion's mane to mice on a high-fat diet for 28 days. Without any changes in diet, body fat percentage and levels of triacylglycerol (a type of fat found in the blood) decreased.

Another study came to a similar conclusion. Lion's mane decreased levels of low-density, bad cholesterol (LDL), and increased levels of high-density, good cholesterol (HDL) in rats. 

lion's mane for heart health

Lion’s Mane Mental and Spiritual Benefits

Nearly one in five Americans lives with some form of mental health issue, most commonly anxiety or depression. Whether you're struggling with mental health problems yourself, want to reap the spiritual benefits of lion's mane, or just want to achieve more mental clarity and focus, research suggests lion's mane can help you in your quest.

Lion’s Mane for Clarity and Focus

A few studies show promising results when it comes to using lion's mane for memory, overall brain health, clarity, and focus.

For example, an animal study published in 2017 looked at the effects of the mushroom on neuronal health and memory. The results show lion's mane significantly increased recognition memory, nerve growth, and neurotransmission in healthy mice.

A previously-mentioned study found that:

“In a behavior test on wild-type mice, oral supplementation with H. erinaceus induced a statistically significant improvement in spatial short-term and visual recognition memory.”

Another study examined the effects of medicinal mushrooms, Hericium erinaceus included, on aging brains. Although it was an in vitro study, the results indicate improvement in cognitive functions from daily lion’s mane consumption.

Lion’s Mane and Anxiety

Lion's mane seems to reduce anxiety, as well as lessen the symptoms of many other mental health issues. A recent animal study found that “mice receiving H. erinaceus had…increased exploratory behavior toward novel objects,” which is indicative of lower levels of anxiety in these animals.

2010 study investigated the clinical effects of lion's mane on various symptoms of menopause, including anxiety. Half of the 30 women in the study were given cookies that contained the mushroom, while medical reviewers gave the other half a placebo.

After four weeks, the participants taking the mushroom reported better mental health. They scored lower than the placebo group on psychological tests that measure irritability and anxiety.

Another study looked at the effects of Hericium erinaceus extract on depression and anxiety. Results show that the mushroom extract reduces depressive and anxious behaviors by promoting the growth of new nerve cells in the hippocampus.

Lion’s Mane and Depression

The research on lion's mane and depression shows promising results. A scientific article on the therapeutic potential of lion’s mane for depressive disorders found that: 

“Based on the neurotrophic and neurogenic pathophysiology of depression, H. erinaceus may be a potential alternative medicine for the treatment of depression.”

This scientific article, published in 2020, took a critical look at the research linking lion's mane and depression. Although still at an early stage, this research demonstrates that lion's mane significantly relieves depressive episodes through monoaminergic regulation.

Erinacine, one of the bioactive compounds found in lion's mane, could be an active agent in the treatment of depressive disorders. A 2018 study showed that erinacine produces antidepressant effects by modulating certain pathways and blocking NF-kB signals in mice.

To learn more about how lion’s mane can help you reduce symptoms of depression, read our article on lion’s mane and depression.

lion's mane for mental health

Lion’s Mane and ADHD

There isn't a lot of research on lion's mane and ADHD, but the mushroom has demonstrated potential benefits for focus and memory. Given that ADHD involves compromised focus and memory, it's possible that lion's mane may benefit people living with this condition.

Many people with ADHD also use lion’s mane due to its ability to alleviate symptoms of mental health disorders that often accompany ADHD, such as anxiety and depression.

To learn more, read our article on the benefits of lion’s mane on attention deficit hyperactivity disorder and also check out our Adderall and lion’s mane comparison.

Lion’s Mane and Gut Health

Lion’s mane shows promise for promoting digestive health.

In a recent study, researchers demonstrated that “H. erinaceus extracts could promote the growth of beneficial gut bacteria…which shows clinical potential in relieving irritable bowel disease by regulating gut microbiota and immune system.”

Lion’s Mane and H. Pylori

Helicobacter pylori is a type of bacteria that causes ulcers in the stomach and intestines. In some instances, these infections can even contribute to stomach cancer.

Several studies examined how Hericium erinaceus may inhibit Helicobacter pylori. One revealed that ethanol extracts from lion's mane hindered the production of these harmful gut bacteria.

An in vitro study from 2013 came to a similar conclusion. A medicinal mushroom supplement made of 14 mushroom species, including lion's mane, inhibited the growth of H. pylori in an isolated cell.

Lion’s Mane and Ulcerative Colitis

randomized, single-blind, placebo-controlled study examined the effects of a mushroom extract on ulcerative colitis. The extract contained several mushrooms, including lion's mane.

The results concluded that the extract had beneficial effects on symptoms of ulcerative colitis. It was particularly useful in mild to moderate cases, and for those who used conventional medication in addition to the extract.

Lion’s Mane and Diabetes

Hericium erinaceus polysaccharides possess various bioactive benefits, including anti-hyperglycemic properties. Essentially, these lion’s mane compounds can help lower blood sugar levels—quite useful for those with diabetes.

2013 study looked at the effects of a water-soluble extract of lion's mane in rats with diabetes. After 28 days on the medicinal mushrooms, blood glucose levels in the subject rats lowered significantly.

Another study looked at the protective effects of Hericium erinaceus on neuropathic pain caused by diabetes. Levels of pain improved in rats after taking a lion's mane supplement for six weeks.

To learn more about taking lion’s mane as a diabetic, take a look at our article on the benefits of Hericium erinaceus on diabetes.

lion's mane for diabetes

Lion’s Mane and Cancer

Many medicinal mushrooms exhibit incredible anti-tumor potential, including lion's mane. A previously mentioned study cites that“four different polysaccharides isolated from the H. erinaceus sporocarp show antitumor activity: xylans, glucoxylans, heteroxyloglucans, and galactoxyloglucans.”

Cerebrosides found in lion's mane fruiting bodies could also be beneficial for cancer patients. A recent study assessed how cerebroside E, a compound found in lion’s mane,  can aid in cancer treatment. The compound was shown to slow down the growth of new cancer cells by inhibiting the formation of new blood vessels that would supply the cancer cells with blood.

Hericium erinaceus also contains phytochemicals (bioactive compounds) that may have therapeutic potential against certain types of cancer, including leukemia and breast cancer.

Lion's mane may also possess antimetastatic activity, especially for lung cancer metastasis. A 2013 study found that the mushroom strongly elicited cancer cell death by inhibiting metastasis of cancer cells.

If we were to list every study on the benefits of lion’s mane on various types of cancer, we’d be here all day. To learn more, read our detailed review of lion’s mane cancer benefits.

Lion’s Mane and the Immune System

An animal study investigated the effects of lion's mane polysaccharides on immune health in mice. Results suggest that Hericium erinaceus improves immune function by enhancing both cell and humoral immunity.

The medicinal fungus can also aid in the regulation of the gut microbiome. A 2017 study revealed that a protein isolated from lion's mane acted as a probiotic and was beneficial for metabolism, in general. Given that the gut plays a major role in the immune system, a healthy gut microbiome is crucial for optimal immune health.

Another study looked at the potential antibacterial effects of Hericium erinaceus in mice. The results suggest that the lion's mane mushroom extract activated innate immune cells, thus helping the body fight bacterial infections.

Hericium erinaceus also appears to aid in battling fungal infections, a common issue people with poor immune systems face, according to a 2022 study on lion’s mane and Candida albicans. This study found that lion’s mane “reduced the damage of C. albicans to the visceral tissue of infected mice and improved the survival rate of mice.”

Lion’s Mane to Fight Inflammation

Antioxidant properties and the ability to fight inflammation are among the many benefits of lion's mane mushrooms. A 2014 study found that water-soluble oligosaccharides found in Hericium erinaceus had incredible antioxidant activity. Another study, published in 2022, examined the antiinflammatory potential of four compounds found in lion’s mane:

“The four typical aromatic compounds were evaluated for their inhibition effects on the secretion of TNF-α, IL-6 and NO, three major proinflammatory mediators, in the macrophage RAW 264.7 model. Two of them showed moderate inhibitory effects indicating their potential anti-inflammatory activity, which may provide the basis for the traditional medical use of H. erincacus.”

2015 study examined lion's mane mushroom’s ability to reduce inflammation in mice with acute alcohol poisoning. The mice that were taking lion's mane supplements had significantly less severe liver damage than their control counterparts.

“The hepatic histopathological observations showed that [Hericium erinaceus] had a relatively significant role in mice model, which had alcoholic liver damage…(200 mg/kg BW) supplementation could restrain the hepatic damage caused by acute alcohol exposure.”

The lion's mane mushroom contains polysaccharides that can also lessen oxidative stress. A 2012 study found increased antioxidant enzymes in mice after just 15 days of ingesting lion's mane.

To learn more about the anti-inflammatory properties of lion’s mane, take a look at our article on Hericium erinaceus and inflammation.

How to Grow Lion’s Mane Mushrooms

Growing mushrooms yourself can be a fun and rewarding hobby if you’re prepared to devote significant time and resources to it.

If you’re going to attempt growing lion’s mane mushrooms, make sure you’ve got the right sort of facilities in your home or apartment.

You’ll need a cool, damp, dark space. Basements work well, though you can also set up a small mushroom growing operation in a cabinet or a closet.

You have three primary options when it comes to growing lion’s mane mushrooms yourself:

  1. Growing with a kit. Mushroom growing kits are readily available to purchase from various online retailers. This is the easiest option for someone without mushroom growing experience.
  2. Commercially made spawn. You can buy lion’s mane mushroom spawn and cultivate it yourself.
  3. Make your own lion’s mane spawn. This is the most advanced method of growing your own lion’s mane mushrooms. You’ll be spawning your own lion’s mane starting with a pure culture on agar, a jelly-like substance derived from algae.

If you want to try it yourself, this handy tutorial shows you how to get started with a kit.

Still, fungi can be quite fickle, so don't get discouraged if you don't succeed the first time. Until you get the hang of it, you can find your supply of lion's mane at various farmers' markets, with the prices ranging from $8 to $38 per pound.

 Hericium erinaceus

"Lion's mane mushroom" by cricketsblog is licensed under CC BY 2.0

How to Eat Lion’s Mane Mushroom

There are plenty of ways to include lion's mane in your diet. Some of the most common include lion's mane mushroom capsules and lion’s mane mushroom powder or extract.

Alternatively, you can use dry mushrooms in recipes or opt for a fortified food that contains lion's mane. For example, Forij granola contains lion's mane mushroom extract and is extremely tasty as an added bonus!

Lion’s Mane Powder

Lion's mane mushroom powder is one of the most common ways to consume these fungi. You can put the powder in your smoothies, shakes, or simply mix it with water.

Mushroom powders allow you to reap all the lion's mane mushroom benefits. However, if you're not a fan of the earthy mushroom taste of lion's mane, you may want to find alternative ways to consume lion’s mane.

Lion’s Mane Mushroom Supplement

You can get a lion's mane mushroom supplement in many forms, with mushroom capsules being the most popular choice. You can take a lion’s mane capsule with your daily vitamins in the morning and reap the benefits of the mushroom all day. However, if you often forget to take your supplements, this option may not be the right choice for you.

Lion’s Mane Mushrooms Recipes

If you're a fan of mushrooms, try a few mushroom recipes out yourself. There are plenty of lion's mane mushroom recipe options to choose from, so you can experiment until you find ones you like.

Lion’s Mane Tea 

You can make lion's mane tea out of a powder supplement or buy a pre-made tea mix. If you're using a powder, pour a cup of boiling water over a teaspoon of it and let it steep for about 10 minutes. Alternatively, if you're using a pre-made mix, follow the instructions provided to you by the manufacturer.

Forij Superfood Granola

Researchers suggest that lion's mane should be taken every day for at least two weeks if you want to reap its many benefits. And, is there a better way to get your daily dose of the fungus than a bowl of delicious cereal?

Forij offers healthy granola in three flavors: cinnamon, sunflower seed cacao, and vanilla almond. In one bowl of cereal, you'll get your daily dose of lion's mane mushroom.

Forij granola uses a high-quality lion's mane extract made from whole medicinal mushrooms. Our dual extraction method extracts both water-soluble beta-glucans as well as alcohol-soluble triterpenes. Our decoction process breaks down indigestible chitin cell walls of the mushroom to get much more of these compounds out than ordinary processes do.

One serving of our granola provides 250 mg of hyperconcentrated lion's mane extract, which is eight times more concentrated than a regular lion’s mane supplement. Therefore, you get as much lion's mane potency as you would if you were taking a 2000 mg mushroom powder supplement, all in one bowl of granola.

Can You Eat Lion’s Mane Raw?

Yes, you can eat lion's mane mushrooms raw. However, you may not reap all of the benefits of lion's mane this way.

Since raw fungi are difficult to digest, your body may not absorb all of the nutrients.

If your gut has difficulty with uncooked vegetables, the mushroom may also give you gastrointestinal issues. If that happens, try taking lion's mane with food, preferably breakfast, to avoid gut problems. It’s better to take lion's mane mushrooms in the morning, as doing so will make you feel energized and focused throughout the day.

Lion’s Mane Mushroom Side Effects

Research suggests that lion's mane mushrooms are safe to consume, even at high doses. Still, be cautious if you have a history of allergies, especially to other types of fungi, mold, or yeast. Read our full article on side effects of lion’s mane to learn more about this topic.

Lion’s Mane Drug Interactions

Lion's mane appears to interact with certain prescription drugs, such as blood clotting medication. Since Hericium erinaceus can slow down blood clotting, it may increase your chances of bleeding or bruising if you're on medication that also prevents blood clotting, such as aspirin.

Lion’s Mane Addiction

You can't get addicted to lion's mane mushrooms. Lion's mane does not get you high and poses no risk of addiction, even if you consume it every day. If you stop using the mushrooms, you won't experience symptoms of withdrawal or other problems.

Interested in Trying Lion’s Mane?

Although there is no definitive proof that this fungus can treat, cure, or prevent any disease on its own, there is plenty of research on the many health benefits of lion's mane. If you're interested in experiencing the full spectrum of benefits this mushroom can offer, you can't go wrong withForij Superfood Granola.

Forij granola is gluten-free, vegan, and full of mushroom nutrients. Who knew you could improve your focus, energy, and overall health just by eating delicious cereal?

Forij Superfood Granola

Lion’s Mane Mushroom FAQ

How does lion’s mane make you feel?

Lion's mane does not give you a high in the psychotropic sense. However, it can positively affect your brain function. Regular use of lion's mane can lead to a decrease in depression and anxiety symptoms. Additionally, the mushroom may make you feel more relaxed, as well as improve your focus and memory.

How soon do you feel the effects of lion's mane?

Like with any herbal supplement, it may take a while before you notice the improving effects of lion's mane mushrooms. You will need to use it regularly for at least two weeks before you notice a difference in your overall well-being. And, of course, the longer you use it, the more pronounced the benefits will be.

Can I take lion’s mane every day?

Yes, it is perfectly safe to take lion's mane mushrooms on a daily basis, even in high doses. However, if you're concerned about lion's mane contraindications or if you are allergic to certain fungi, mold, or yeast, make sure to talk to your healthcare professional if you notice any side effects.

Is lion's mane healthy?

Lion's mane mushrooms are among the healthiest foods you could possibly find on the planet. Hericium erinaceus was shown to improve digestion, alleviate symptoms of various mental health issues, and even prevent cancer. This mushroom is a great addition to your diet, but you can also give lion's mane to your children.

Can I take reishi and lion’s mane together?

When it comes to mushrooms, the whole is greater than the sum of its parts. Medicinal mushrooms such as the maitake mushroom, hedgehog mushroom, lion's mane, turkey tail, and reishi mushrooms each have their own sets of benefits.

Therefore, we always suggest taking more than one medicinal fungus, as combining them can only lead to a fuller range of benefits, including neuronal health and more.

Can I buy certified organic lion’s mane mushrooms?

Yes, there are many sources for certified organic mushrooms, including lion’s mane. You can find them online, as well as in most major cities.

Does lion's mane make you high?

No, lion’s mane can’t get you high. Mushrooms that can cause a high contain a compound called psilocybin, a naturally occurring psychedelic that can alter your state of mind.

As lion’s mane does not contain psilocybin or other psychoactive compounds, there is no risk of you getting high from consuming the fungus.

Is lion's mane a poisonous mushroom?

No, lion's mane is not a poisonous mushroom. You can eat as much of this fungus as your heart desires. Plus, due to its distinct appearance, it's unlikely you'll mistake Hericium erinaceus for any poisonous mushroom.

Can lion's mane cause anxiety?

No, lion's mane doesn't appear to cause anxiety. On the contrary, lion's mane mushrooms seem to reduce mild symptoms of anxiety and depression. In addition to its ability to make you feel more relaxed and focused, lion's mane mushrooms may be able to improve anxiety-related symptoms of OCD, as well as sleep problems, a common symptom of anxiety disorders.

Is lion's mane mushroom a psychedelic?

Lion’s mane is not psychedelic and won’t make you hallucinate. Therefore, it’s completely safe to take these medicinal mushrooms during your workday, as they won’t impair your cognitive abilities.

Does lion's mane give you energy?

Yes, lion's mane can be a great source of energy. This fungus can give you a natural energy boost but won't cause a midday energy crash, unlike caffeinated beverages such as coffee and green tea.

Can lion's mane cure a migraine?

While it may not cure them, lion's mane was shown to be quite effective at alleviating migraines. If you experience frequent migraines, you could try taking lion's mane to lessen their severity.

Can lion's mane help with arthritis?

Yes, lion's mane mushrooms appear to be incredibly beneficial for people with arthritis. This mushroom can alleviate pain and inflammation related to this ailment.

Is lion's mane good for the skin?

Yes, lion's mane is good for the skin. For example, research shows that Hericium erinaceus can aid in acne treatment. And, even if you don't have acne, lion's mane can help your skin look glowy and supple.

Can I take lion's mane while pregnant?

Centuries of use and anecdotal evidence suggest that lion's mane is safe to take while pregnant. However, due to the lack of scientific research on the effects of lion's mane on breastfeeding and pregnancy, many women choose not to take this mushroom while pregnant and breastfeeding.

How much lion’s mane should I take?

There is no ideal lion’s mane dosage that’s perfect for every person and all health conditions. It’s best to start with a low to medium dosage of around 500 mg and work your way up until you notice an improvement. For more information about taking lion’s mane for specific health issues, read our lion’s mane dosage guide.

Should athletes take lion’s mane?

Yes, athletes can benefit from taking lion’s mane mushrooms as a preworkout supplement. These mushrooms have energizing properties and can aid in muscle recovery, as well as help you create a mind-muscle connection thanks to their focus-enhancing properties.

To read more about these benefits, read our article on lion’s mane for athletes and one on the benefits of lion’s mane for bodybuilders.

Resources

  1. Jiang, S. (2014). Medicinal properties of Hericium erinaceus and its potential to formulate novel mushroom-based pharmaceuticals. Applied Microbiology and Biotechnology, 98(18), 7661–7670. https://doi.org/10.1007/s00253-014-5955-5
  2. Kim, K. H. (2012). Isohericenone, a new cytotoxic isoindolinone alkaloid from Hericium erinaceum. The Journal of Antibiotics, 65(11), 575–577. https://doi.org/10.1038/ja.2012.65
  3. Spelman, K. (2017). Neurological Activity of Lion’s Mane (Hericium erinaceus). Journal of Restorative Medicine, 6(1), 19–26. https://doi.org/10.14200/jrm.2017.6.0108
  4. Lai, P. L. (2013). Neurotrophic Properties of the Lion’s Mane Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. International Journal of Medicinal Mushrooms, 15(6), 539–554. https://doi.org/10.1615/intjmedmushr.v15.i6.30
  5. Martínez‐Mármol, R. (2023). Hericerin derivatives activates a pan‐neurotrophic pathway in central hippocampal neurons converging to ERK1 /2 signaling enhancing spatial memory. Journal of Neurochemistry. https://doi.org/10.1111/jnc.15767
  6. Wong, K-H. (2011). Peripheral Nerve Regeneration Following Crush Injury to Rat Peroneal Nerve by Aqueous Extract of Medicinal Mushroom Hericium erinaceus (Bull.: Fr) Pers. (Aphyllophoromycetideae). Evidence-Based Complementary and Alternative Medicine, 2011, 1–10. https://doi.org/10.1093/ecam/neq062
  7. Kolotushkina, E. V. (2003). The influence of Hericium erinaceus extract on myelination process in vitro. Fiziolohichnyi zhurnal (Kiev, Ukraine: 1994), 49(1), 38–45. https://pubmed.ncbi.nlm.nih.gov/12675022/
  8. Yanshree (2022). The Monkey Head Mushroom and Memory Enhancement in Alzheimer’s Disease. Cells, 11(15), 2284. https://doi.org/10.3390/cells11152284
  9. Zhang, J. (2016). The Neuroprotective Properties of Hericium erinaceus in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer’s Disease Mouse Model. International Journal of Molecular Sciences, 17(11), 1810. https://doi.org/10.3390/ijms17111810
  10. Tsai-Teng, T. (2016). Erinacine A-enriched Hericium erinaceus mycelium ameliorates Alzheimer’s disease-related pathologies in APPswe/PS1dE9 transgenic mice. Journal of Biomedical Science, 23(1). https://doi.org/10.1186/s12929-016-0266-z
  11. Park, Y.S. (2002) Effect of an exo-polysaccharide from the culture broth of Hericium erinaceus on enhancement of growth and differentiation of rat adrenal nerve cells. Cytotechnology 39, 155–162. https://doi.org/10.1023/A:1023963509393
  12. D’Amico, R., Trovato Salinaro, A., Fusco, R., Cordaro, M., Impellizzeri, D., Scuto, M., Ontario, M. L. (2021). Hericium erinaceus and Coriolus versicolor Modulate Molecular and Biochemical Changes after Traumatic Brain Injury. Antioxidants, 10(6), 898. https://doi.org/10.3390/antiox10060898
  13. Lee, K. F. (2020). Post-Treatment with Erinacine A, a Derived Diterpenoid of H. erinaceus, Attenuates Neurotoxicity in MPTP Model of Parkinson’s Disease. Antioxidants, 9(2), 137. https://doi.org/10.3390/antiox9020137
  14. Friedman, M. (2015). Chemistry, Nutrition, and Health-Promoting Properties of Hericium erinaceus (Lion’s Mane) Mushroom Fruiting Bodies and Mycelia and Their Bioactive Compounds. Journal of Agricultural and Food Chemistry, 63(32), 7108–7123. https://doi.org/10.1021/acs.jafc.5b02914
  15. Lee, K. F. (2014). Protective Effects of Hericium erinaceus Mycelium and Its Isolated Erinacine A against Ischemia-Injury-Induced Neuronal Cell Death via the Inhibition of iNOS/p38 MAPK and Nitrotyrosine. International Journal of Molecular Sciences, 15(9), 15073–15089. https://doi.org/10.3390/ijms150915073
  16. Rahman, M. A. (2014). Inhibitory Effect on In Vitro LDL Oxidation and HMG Co-A Reductase Activity of the Liquid-Liquid Partitioned Fractions ofHericium erinaceus(Bull.) Persoon (Lion’s Mane Mushroom). BioMed Research International, 2014, 1–9. https://doi.org/10.1155/2014/828149
  17. Mori, K. (2010). Inhibitory effect of hericenone B from Hericium erinaceus on collagen-induced platelet aggregation. Phytomedicine, 17(14), 1082–1085. https://doi.org/10.1016/j.phymed.2010.05.004
  18. Hiwatashi, K. (2010). Yamabushitake Mushroom (Hericium erinaceus) Improved Lipid Metabolism in Mice Fed a High-Fat Diet. Bioscience, Biotechnology, and Biochemistry, 74(7), 1447–1451. https://doi.org/10.1271/bbb.100130
  19. Choi, W. S. (2013). Hypolipidaemic Effect of Hericium erinaceum Grown in Artemisia capillaris on Obese Rats. Mycobiology, 41(2), 94–99. https://doi.org/10.5941/myco.2013.41.2.94
  20. Brandalise, F. Dietary Supplementation of Hericium erinaceus Increases Mossy Fiber-CA3 Hippocampal Neurotransmission and Recognition Memory in Wild-Type Mice. Evidence-Based Complementary and Alternative Medicine, 2017, 1–13. https://doi.org/10.1155/2017/3864340
  21. Sabaratnam, V. (2013). Neuronal Health – Can Culinary and Medicinal Mushrooms Help? Journal of Traditional and Complementary Medicine, 3(1), 62–68. https://doi.org/10.4103/2225-4110.106549
  22. Rodriguez, M. N. (2022). Lion’s Mane (Hericium erinaceus) Exerts Anxiolytic Effects in the rTg4510 Tau Mouse Model. Behavioral Sciences, 12(7), 235. https://doi.org/10.3390/bs12070235
  23. Nagano, M. (2010). Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. Biomedical Research, 31(4), 231–237. https://doi.org/10.2220/biomedres.31.231
  24. Ryu, S. (2018). Hericium erinaceus Extract Reduces Anxiety and Depressive Behaviors by Promoting Hippocampal Neurogenesis in the Adult Mouse Brain. Journal of Medicinal Food, 21(2), 174–180. https://doi.org/10.1089/jmf.2017.4006
  25. Chong, P. S. (2019). Therapeutic Potential of Hericium erinaceus for Depressive Disorder. International Journal of Molecular Sciences, 21(1), 163. https://doi.org/10.3390/ijms21010163
  26. Chiu, C. H. (2018). Erinacine A-Enriched Hericium erinaceus Mycelium Produces Antidepressant-Like Effects through Modulating BDNF/PI3K/Akt/GSK-3β Signaling in Mice. International Journal of Molecular Sciences, 19(2), 341. https://doi.org/10.3390/ijms19020341
  27. Diling, C. (2017). Extracts from Hericium erinaceus relieve inflammatory bowel disease by regulating immunity and gut microbiota. Oncotarget, 8(49), 85838–85857. https://doi.org/10.18632/oncotarget.20689
  28. Liu, J. H. (2016). Anti- Helicobacter pylori activity of bioactive components isolated from Hericium erinaceus. Journal of Ethnopharmacology, 183, 54–58. https://doi.org/10.1016/j.jep.2015.09.004
  29. Shang, X. (2013). In Vitro Anti-Helicobacter pylori Effects of Medicinal Mushroom Extracts, with Special Emphasis on the Lion’s Mane Mushroom, Hericium erinaceus (Higher Basidiomycetes). International Journal of Medicinal Mushrooms, 15(2), 165–174. https://doi.org/10.1615/intjmedmushr.v15.i2.50
  30. Therkelsen, S. P. (2016). Effect of a Medicinal Agaricus blazei Murill-Based Mushroom Extract, AndoSanTM, on Symptoms, Fatigue and Quality of Life in Patients with Ulcerative Colitis in a Randomized Single-Blinded Placebo Controlled Study. PLOS ONE, 11(3), e0150191. https://doi.org/10.1371/journal.pone.0150191
  31. Liang, B. (2013). Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats. BMC Complementary and Alternative Medicine, 13(1). https://doi.org/10.1186/1472-6882-13-253
  32. Yi, Z. (2015). Protective Effect of Ethanol Extracts of Hericium erinaceus on Alloxan-Induced Diabetic Neuropathic Pain in Rats. Evidence-Based Complementary and Alternative Medicine, 2015, 1–5. https://doi.org/10.1155/2015/595480
  33. Lee, S. R. (2015). A new cerebroside from the fruiting bodies of Hericium erinaceus and its applicability to cancer treatment. Bioorganic & Medicinal Chemistry Letters, 25(24), 5712–5715. https://doi.org/10.1016/j.bmcl.2015.10.092
  34. Kim, S. P. (2011). Mechanism of Lion’s Mane Mushroom (Yamabushitake, Hericium erinaceus) mushroom-induced apoptosis of U937 human monocytic leukemia cells. Food & Function, 2(6), 348. https://doi.org/10.1039/c1fo10030k
  35. Kim, S. P. (2013). Hericium erinaceus (Lion’s Mane) Mushroom Extracts Inhibit Metastasis of Cancer Cells to the Lung in CT-26 Colon Cancer-Tansplanted Mice. Journal of Agricultural and Food Chemistry, 61(20), 4898–4904. https://doi.org/10.1021/jf400916c
  36. Sheng, X. (2017). Immunomodulatory effects of Hericium erinaceus derived polysaccharides are mediated by intestinal immunology. Food & Function, 8(3), 1020–1027. https://doi.org/10.1039/c7fo00071e
  37. Diling, C. (2017). Immunomodulatory Activities of a Fungal Protein Extracted from Hericium erinaceus through Regulating the Gut Microbiota. Frontiers in Immunology, 8. https://doi.org/10.3389/fimmu.2017.00666
  38. Kim, S. P. (2012). Hericium erinaceus Mushroom Extracts Protect Infected Mice against Salmonella Typhimurium-Induced Liver Damage and Mortality by Stimulation of Innate Immune Cells. Journal of Agricultural and Food Chemistry, 60(22), 5590–5596. https://doi.org/10.1021/jf300897w
  39. Qian, Z. (2022). Natural Compound 2-Chloro-1,3-dimethoxy-5-methylbenzene, Isolated from Hericium Erinaceus, Inhibits Fungal Growth by Disrupting Membranes and Triggering Apoptosis. Journal of Agricultural and Food Chemistry, 70(21), 6444–6454. https://doi.org/10.1021/acs.jafc.2c01417
  40. Hou, Y. (2014). Composition and antioxidant activity of water-soluble oligosaccharides from Hericium erinaceus. Molecular Medicine Reports, 11(5), 3794–3799. https://doi.org/10.3892/mmr.2014.3121
  41. Xie, G. (2022). Secondary Metabolites from Hericium erinaceus and Their Anti-Inflammatory Activities. Molecules, 27(7), 2157. https://doi.org/10.3390/molecules27072157
  42. Hao, L. (2015). Protective Effect of Hericium erinaceus on Alcohol Induced Hepatotoxicity in Mice. Evidence-Based Complementary and Alternative Medicine, 2015, 1–5. https://doi.org/10.1155/2015/418023
  43. Han, Z. H. (2013). Evaluation of in vivo antioxidant activity of Hericium erinaceus polysaccharides. International Journal of Biological Macromolecules, 52, 66–71. https://doi.org/10.1016/j.ijbiomac.2012.09.009

Forij Disclaimer

The information provided in this article is not intended to diagnose, treat, or cure any disease or illness and should not be taken as medical advice. The statements contained herein have not been evaluated by the Food and Drug Administration (FDA). Before adding lion’s mane to your health and wellness routine, talk to a health care professional about the potential benefits, side effects, and uses of this mushroom.

Search